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KMID : 0861420100140020150
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Korean Journal of Nuclear Medicine Technology
2010 Volume.14 No. 2 p.150 ~ p.154
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Comparison of the Ejection Fraction Between Gated Blood Pool, Gated Blood Pool SPECT and Echocardiography
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Jung Ji-Wook
Lee Hyo-Yeong
Yun Jong-Jun
Lee Hwa-Jin
Lee Mu-Seok
Song Hyeon-Seok
Park Se-Yun
Kim Jae-Hwan
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Abstract
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Purpose: Ejection fraction (EF) is one of the most important factors that evaluate heart function. Recently,
according to echocardiography and myocardial perfusion SPECT, the number of gated blood pool scan (planar GBP) is declining. Measurement of left ventricular ejection fraction using gated blood pool SPECT (GBPS) is known as relatively correspond with echocardiography. We compared EF derived from plnar GBP, GBPS and echocadiography using modified simpson method to determine the accuracy.
Materials and Methods: From January 2007 to June 2010, planar GBP and GBPS were performed on 34 patients who admitted to Pusan National University Hospital (men 23, women 11, mean age 52.6±27.2). Each patient was injected with 99mTcO4 -of 20 mCi after pyrophosphate injection and then scanned using both planar GBP and GBPS techniques. For
image analysis, we use ADAC Laboratories, Ver. 4.20 software. The result analyzed was processed by SPSS 17.0 Win statistic program and statistical method applied in data analysis is one-way anova, Tukey’s post hoc test, pearson correlation test.
Results: One-way anova test show no significant difference (planar GBP 56.3±13.9%; GBPS 60.4±16.0%; echocardiography 59.1±14.4%, p=0.486, p>0.05). Tukey’s post hoc test show no significant difference (planar GBP-echocardiography p=0.697; GBPS-echocardiography p=0.928; planar GBP-GBPS p=0.469, p>0.05). Values for EF obtained with planar GBP and GBPS correlated well with those obtained with echocardiography (planar-echocardiography r=0.697; GBPS-echocardiography r=0.928; planar GBP-GBPS r=0.469).
Conclusion: The problems of accuracy and reproducibility for planar GBP still remain. But planar GBP is a safe and non-invasive method. In addition, planar GBP is useful to evaluate patient with low resolution echocardiography images. GBPS is not appicated clinically. but GBPS can be obtain various left ventricular functional parameters. planar GBP, GBPS and echocardiography show a good correlation between each other. Therefore, planar GBP and GBPS are useful for evaluating left ventricular ejection fraction.
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KEYWORD
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Gated blood pool scan (planar GBP), Gated blood pool SPECT (GBPS), Ejection fraction (EF), Echocardiography
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